HER2-Specific Pseudomonas Exotoxin A PE25 Based Fusions: Influence of Targeting Domain on Target Binding, Toxicity, and In Vivo Biodistribution

The human epidermal growth factor receptor 2 (HER2) is a clinically validated target for cancer therapy, and targeted therapies are often used in regimens for patients with a high HER2 expression level. Despite the success of current drugs, a number of patients succumb to their disease, which motiva...

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Detalles Bibliográficos
Autores principales: Ding, Haozhong, Altai, Mohamed, Yin, Wen, Lindbo, Sarah, Liu, Hao, Garousi, Javad, Xu, Tianqi, Orlova, Anna, Tolmachev, Vladimir, Hober, Sophia, Gräslund, Torbjörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238247/
https://www.ncbi.nlm.nih.gov/pubmed/32344762
http://dx.doi.org/10.3390/pharmaceutics12040391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238247/
https://www.ncbi.nlm.nih.gov/pubmed/32344762
http://dx.doi.org/10.3390/pharmaceutics12040391

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