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Exposure-Response and Clinical Outcome Modeling of Inhaled Budesonide/Formoterol Combination in Asthma Patients

Exposure-response and clinical outcome (CO) model for inhaled budesonide/formoterol was developed to quantify the relationship among pharmacokinetics (PK), pharmacodynamics (PD) and CO of the drugs and evaluate the covariate effect on model parameters. Sputum eosinophils cationic proteins (ECP) and...

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Detalles Bibliográficos
Autores principales: Back, Hyun-moon, Lee, Jong Bong, Kim, Anhye, Park, Seon-Jong, Kim, Junyeong, Chae, Jung-woo, Sheen, Seung Soo, Kagan, Leonid, Park, Hae-Sim, Ye, Young-Min, Yun, Hwi-yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238265/
https://www.ncbi.nlm.nih.gov/pubmed/32283726
http://dx.doi.org/10.3390/pharmaceutics12040336