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Exposure-Response and Clinical Outcome Modeling of Inhaled Budesonide/Formoterol Combination in Asthma Patients
Exposure-response and clinical outcome (CO) model for inhaled budesonide/formoterol was developed to quantify the relationship among pharmacokinetics (PK), pharmacodynamics (PD) and CO of the drugs and evaluate the covariate effect on model parameters. Sputum eosinophils cationic proteins (ECP) and...
Autores principales: | Back, Hyun-moon, Lee, Jong Bong, Kim, Anhye, Park, Seon-Jong, Kim, Junyeong, Chae, Jung-woo, Sheen, Seung Soo, Kagan, Leonid, Park, Hae-Sim, Ye, Young-Min, Yun, Hwi-yeol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238265/ https://www.ncbi.nlm.nih.gov/pubmed/32283726 http://dx.doi.org/10.3390/pharmaceutics12040336 |
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