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High-throughput screening of clinically approved drugs that prime nonviral gene delivery to human Mesenchymal stem cells

BACKGROUND: Human mesenchymal stem cells (hMSCs) are intensely researched for applications in cell therapeutics due to their unique properties, however, intrinsic therapeutic properties of hMSCs could be enhanced by genetic modification. Viral transduction is efficient, but suffers from safety issue...

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Detalles Bibliográficos
Autores principales: Kozisek, Tyler, Hamann, Andrew, Nguyen, Albert, Miller, Michael, Plautz, Sarah, Pannier, Angela K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238544/
https://www.ncbi.nlm.nih.gov/pubmed/32467728
http://dx.doi.org/10.1186/s13036-020-00238-1