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Mesenchymal stem cells combined with liraglutide relieve acute lung injury through apoptotic signaling restrained by PKA/β-catenin

BACKGROUND: ARDS and ALI are life-threatening diseases with extremely high mortality in patients. Different sources of MSCs could mitigate the symptoms of ALI from diverse mechanisms. Liraglutide is an activator of glucagon-like peptide-1 receptor (GLP-1R) that activates anti-apoptotic pathways and...

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Detalles Bibliográficos
Autores principales: Yang, Xiaotong, Ma, Xiaoying, Don, Ocholi, Song, Yuanlin, Chen, Xiaoyan, Liu, Jianwen, Qu, Jieming, Feng, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238586/
https://www.ncbi.nlm.nih.gov/pubmed/32429994
http://dx.doi.org/10.1186/s13287-020-01689-5