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Rno-microRNA-30c-5p promotes myocardial ischemia reperfusion injury in rats through activating NF-κB pathway and targeting SIRT1

BACKGROUND: This study aimed to investigate the regulatory effect of rno-microRNA-30c-5p (rno-miR-30c-5p) on myocardial ischemia reperfusion (IR) injury in rats and the underlying molecular mechanisms. METHODS: A rat model of myocardial IR injury was established. The infarct size was detected by 2,3...

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Detalles Bibliográficos
Autores principales: Chen, Jianfeng, Zhang, Mingming, Zhang, Shouyan, Wu, Junlong, Xue, Shufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238603/
https://www.ncbi.nlm.nih.gov/pubmed/32434515
http://dx.doi.org/10.1186/s12872-020-01520-2