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Engraftment of human induced pluripotent stem cell-derived myogenic progenitors restores dystrophin in mice with duchenne muscular dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is a devastating genetic muscular disorder with no effective treatment that is caused by the loss of dystrophin. Human induced pluripotent stem cells (hiPSCs) offer a promising unlimited resource for cell-based therapies of muscular dystrophy. However, t...

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Detalles Bibliográficos
Autores principales: He, Ruojie, Li, Huan, Wang, Liang, Li, Yaqin, Zhang, Yu, Chen, Menglong, Zhu, Yuling, Zhang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238630/
https://www.ncbi.nlm.nih.gov/pubmed/32430065
http://dx.doi.org/10.1186/s40659-020-00288-1