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In vitro evaluation of double carbapenem and colistin combinations against OXA-48, NDM carbapenemase-producing colistin-resistant Klebsiella pneumoniae strains

BACKGROUND: Treatment of pandrug-resistant isolates often necessitates combination therapy. Checkerboard synergy and time-killing assay tests were performed to evaluate the benefits of a triple combination with meropenem, ertapenem, and colistin against 10 colistin-resistant K. pneumoniae clinical i...

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Detalles Bibliográficos
Autores principales: Erdem, Fatma, Abulaila, Ayham, Aktas, Zerrin, Oncul, Oral
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238654/
https://www.ncbi.nlm.nih.gov/pubmed/32430058
http://dx.doi.org/10.1186/s13756-020-00727-4