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Tetramethylpyrazine enhanced the therapeutic effects of human umbilical cord mesenchymal stem cells in experimental autoimmune encephalomyelitis mice through Nrf2/HO-1 signaling pathway

INTRODUCTION: The therapeutic effects of mesenchymal stem cells (MSCs) have been limited by their apoptosis induced by oxidative stress after delivery into the injured sites. Therefore, strategies designed to improve the MSC therapeutic efficacy need to be explored. Tetramethylpyrazine (TMP) can pro...

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Detalles Bibliográficos
Autores principales: Zhang, Lianshuang, Wang, Xifeng, Lu, Xueyan, Ma, Yanchao, Xin, Xin, Xu, Xiaomin, Wang, Siyuan, Hou, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238657/
https://www.ncbi.nlm.nih.gov/pubmed/32430010
http://dx.doi.org/10.1186/s13287-020-01700-z