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Nucleotide Analogues as Inhibitors of SARS-CoV-2 Polymerase

SARS-CoV-2, a member of the coronavirus family, is responsible for the current COVID-19 pandemic. Based on our analysis of hepatitis C virus and coronavirus replication, and the molecular structures and activities of viral inhibitors, we previously demonstrated that three nucleotide analogues inhibi...

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Detalles Bibliográficos
Autores principales: Chien, Minchen, Anderson, Thomas K., Jockusch, Steffen, Tao, Chuanjuan, Kumar, Shiv, Li, Xiaoxu, Russo, James J., Kirchdoerfer, Robert N., Ju, Jingyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239050/
https://www.ncbi.nlm.nih.gov/pubmed/32511320
http://dx.doi.org/10.1101/2020.03.18.997585