The sequence of human ACE2 is suboptimal for binding the S spike protein of SARS coronavirus 2

The rapid and escalating spread of SARS coronavirus 2 (SARS-CoV-2) poses an immediate public health emergency. The viral spike protein S binds ACE2 on host cells to initiate molecular events that release the viral genome intracellularly. Soluble ACE2 inhibits entry of both SARS and SARS-2 coronaviru...

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Detalles Bibliográficos
Autor principal: Procko, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239051/
https://www.ncbi.nlm.nih.gov/pubmed/32511321
http://dx.doi.org/10.1101/2020.03.16.994236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239051/
https://www.ncbi.nlm.nih.gov/pubmed/32511321
http://dx.doi.org/10.1101/2020.03.16.994236

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