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The sequence of human ACE2 is suboptimal for binding the S spike protein of SARS coronavirus 2
The rapid and escalating spread of SARS coronavirus 2 (SARS-CoV-2) poses an immediate public health emergency. The viral spike protein S binds ACE2 on host cells to initiate molecular events that release the viral genome intracellularly. Soluble ACE2 inhibits entry of both SARS and SARS-2 coronaviru...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239051/ https://www.ncbi.nlm.nih.gov/pubmed/32511321 http://dx.doi.org/10.1101/2020.03.16.994236 |