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Sanguinarine suppresses migration and metastasis in colorectal carcinoma associated with the inversion of EMT through the Wnt/β‐catenin signaling

BACKGROUND: Unresectable lung or liver organ metastases of colorectal carcinoma (CRC) remain a major obstacle in clinical therapeutics. Epithelial to mesenchymal transition (EMT), a major cause of highly frequent metastasis in tumor, can be promoted by the Wnt/β‐catenin pathway that is aberrantly ac...

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Detalles Bibliográficos
Autores principales: Zhu, Man, Gong, Zhengyan, Wu, Qing, Shi, Xianpeng, Su, Qi, Zhang, Yanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239267/
https://www.ncbi.nlm.nih.gov/pubmed/32508048
http://dx.doi.org/10.1002/ctm2.1