Cargando…

Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation

Optimal fludarabine exposure has been associated with improved treatment outcome in allogeneic hematopoietic cell transplantation, suggesting potential benefit of individualized dosing. A randomized controlled trial (RCT) comparing alternative fludarabine dosing strategies to current practice may be...

Descripción completa

Detalles Bibliográficos
Autores principales: Langenhorst, Jurgen B., Dorlo, Thomas P.C., van Kesteren, Charlotte, van Maarseveen, Erik M., Nierkens, Stefan, de Witte, Moniek A., Boelens, Jaap Jan, Huitema, Alwin D.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239337/
https://www.ncbi.nlm.nih.gov/pubmed/31957334
http://dx.doi.org/10.1002/psp4.12486