Modeling Favipiravir Antiviral Efficacy Against Emerging Viruses: From Animal Studies to Clinical Trials

In 2014, our research network was involved in the evaluation of favipiravir, an anti‐influenza polymerase inhibitor, against Ebola virus. In this review, we discuss how mathematical modeling was used, first to propose a relevant dosing regimen in humans, and then to optimize its antiviral efficacy i...

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Detalles Bibliográficos
Autores principales: Madelain, Vincent, Mentré, France, Baize, Sylvain, Anglaret, Xavier, Laouénan, Cédric, Oestereich, Lisa, Nguyen, Thi Huyen Tram, Malvy, Denis, Piorkowski, Géraldine, Graw, Frederik, Günther, Stephan, Raoul, Hervé, de Lamballerie, Xavier, Guedj, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239338/
https://www.ncbi.nlm.nih.gov/pubmed/32198838
http://dx.doi.org/10.1002/psp4.12510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239338/
https://www.ncbi.nlm.nih.gov/pubmed/32198838
http://dx.doi.org/10.1002/psp4.12510

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