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ERp29 as a regulator of Insulin biosynthesis

The environment within the Endoplasmic Reticulum (ER) influences Insulin biogenesis. In particular, ER stress may contribute to the development of Type 2 Diabetes (T2D) and Cystic Fibrosis Related Diabetes (CFRD), where evidence of impaired Insulin processing, including elevated secreted Proinsulin/...

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Detalles Bibliográficos
Autores principales: Viviano, Jeffrey, Brecker, Margaret, Ferrara-Cook, Christine, Suaud, Laurence, Rubenstein, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239452/
https://www.ncbi.nlm.nih.gov/pubmed/32433667
http://dx.doi.org/10.1371/journal.pone.0233502