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High polymerase ε expression associated with increased CD8+T cells improves survival in patients with non-small cell lung cancer
DNA replicase polymerase ε (POLE) is critical in proofreading and correcting errors of DNA replication. Low POLE expression plays a pivotal role in accumulation of mutations and onset of cancer, contributing to development and growth of tumor cells. The aim of this study is to reveal the survival, a...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239475/ https://www.ncbi.nlm.nih.gov/pubmed/32433714 http://dx.doi.org/10.1371/journal.pone.0233066 |