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Targeted pathological collagen delivery of sustained-release rapamycin to prevent heterotopic ossification

Heterotopic ossification (HO) in connective tissues like tendons and ligaments severely damages tissue structure. The pathogenesis of HO remains unclear but may involve mTOR. The results presented here indicate that tendon stem/progenitor cells do not undergo osteochondrogenic differentiation when m...

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Detalles Bibliográficos
Autores principales: Chen, Yangwu, Shen, Weiliang, Tang, Chenqi, Huang, Jiayun, Fan, Chunmei, Yin, Zi, Hu, Yejun, Chen, Weishan, Ouyang, Hongwei, Zhou, Yiting, Mao, Zhengwei, Chen, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239699/
https://www.ncbi.nlm.nih.gov/pubmed/32494667
http://dx.doi.org/10.1126/sciadv.aay9526