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Targeted pathological collagen delivery of sustained-release rapamycin to prevent heterotopic ossification
Heterotopic ossification (HO) in connective tissues like tendons and ligaments severely damages tissue structure. The pathogenesis of HO remains unclear but may involve mTOR. The results presented here indicate that tendon stem/progenitor cells do not undergo osteochondrogenic differentiation when m...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239699/ https://www.ncbi.nlm.nih.gov/pubmed/32494667 http://dx.doi.org/10.1126/sciadv.aay9526 |