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Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians

Most hereditary tumors show aberrations in DNA repair genes or their regulators. In contrast, only a minority of sporadic tumors show alterations in these genes. As a result, genomic instability is currently considered an enhancer of tumorigenesis rather than an obligatory event in this process. How...

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Detalles Bibliográficos
Autores principales: Yadav, Santosh, Anbalagan, Muralidharan, Baddoo, Melody, Chellamuthu, Vinodh K., Mukhopadhyay, Sudurika, Woods, Carol, Jiang, Wei, Moroz, Krzysztof, Flemington, Erik K, Makridakis, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239769/
https://www.ncbi.nlm.nih.gov/pubmed/32300177
http://dx.doi.org/10.1038/s41388-020-1280-x