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Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians
Most hereditary tumors show aberrations in DNA repair genes or their regulators. In contrast, only a minority of sporadic tumors show alterations in these genes. As a result, genomic instability is currently considered an enhancer of tumorigenesis rather than an obligatory event in this process. How...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239769/ https://www.ncbi.nlm.nih.gov/pubmed/32300177 http://dx.doi.org/10.1038/s41388-020-1280-x |