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Rationale and design of the PRAETORIAN-COVID trial: A double-blind, placebo-controlled randomized clinical trial with valsartan for PRevention of Acute rEspiraTORy dIstress syndrome in hospitAlized patieNts with SARS-COV-2 Infection Disease

There is much debate on the use of angiotensin receptor blockers (ARBs) in severe acute respiratory syndrome–coronavirus-2 (SARS-CoV-2)–infected patients. Although it has been suggested that ARBs might lead to a higher susceptibility and severity of SARS-CoV-2 infection, experimental data suggest th...

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Detalles Bibliográficos
Autores principales: Gommans, D. H. Frank, Nas, Joris, Pinto-Sietsma, Sara-Joan, Koop, Yvonne, Konst, Regina E., Mensink, Frans, Aarts, Goaris W.A., Konijnenberg, Lara S.F., Cortenbach, Kimberley, Verhaert, Dominique V.M., Thannhauser, Jos, Mol, Jan-Quinten, Rooijakkers, Maxim J.P., Vos, Jacqueline L., van Rumund, Anouke, Vart, Priya, Hassing, Robert-Jan, Cornel, Jan-Hein, de Jager, C. Peter C., van den Heuvel, Michel M., van der Hoeven, Hans G., Verbon, Annelies, Pinto, Yigal M., van Royen, Niels, van Kimmenade, Roland R.J., de Leeuw, Peter W., van Agtmael, Michiel A., Bresser, Paul, van Gilst, Wiek H., Vonk-Noordergraaf, Anton, Tijssen, Jan G.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239793/
https://www.ncbi.nlm.nih.gov/pubmed/32512291
http://dx.doi.org/10.1016/j.ahj.2020.05.010