Impact of intracellular hemin on N-type inactivation of voltage-gated K(+) channels

N-type inactivation of voltage-gated K(+) channels is conferred by the N-terminal “ball” domains of select pore-forming α subunits or of auxiliary β subunits, and influences electrical cellular excitability. Here, we show that hemin impairs inactivation of K(+) channels formed by Kv3.4 α subunits as...

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Detalles Bibliográficos
Autores principales: Coburger, Ina, Yang, Kefan, Bernert, Alisa, Wiesel, Eric, Sahoo, Nirakar, Swain, Sandip M., Hoshi, Toshinori, Schönherr, Roland, Heinemann, Stefan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Ion Channels, Receptors and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239824/
https://www.ncbi.nlm.nih.gov/pubmed/32388729
http://dx.doi.org/10.1007/s00424-020-02386-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239824/
https://www.ncbi.nlm.nih.gov/pubmed/32388729
http://dx.doi.org/10.1007/s00424-020-02386-1

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