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Impaired differentiation of human induced neural stem cells by TOR1A overexpression
DYT-TOR1A is the most common inherited dystonia caused by a three nucleotide (GAG) deletion (dE) in the TOR1A gene. Death early after birth and cortical anomalies of the full knockout in rodents underscore its developmental importance. We therefore explored the timed effects of TOR1A-wt and TOR1A-dE...
Autores principales: | Stengel, Felix, Vulinovic, Franca, Meier, Britta, Grütz, Karen, Klein, Christine, Capetian, Philipp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239838/ https://www.ncbi.nlm.nih.gov/pubmed/32239467 http://dx.doi.org/10.1007/s11033-020-05390-x |
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