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PGAM5-MAVS interaction regulates TBK1/ IRF3 dependent antiviral responses
Viral infections trigger host innate immune responses, characterized by the production of type-I interferons (IFN) including IFNβ. IFNβ induces cellular antiviral defense mechanisms and thereby contributes to pathogen clearance. Accumulating evidence suggests that mitochondria constitute a crucial p...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239892/ https://www.ncbi.nlm.nih.gov/pubmed/32433485 http://dx.doi.org/10.1038/s41598-020-65155-1 |