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PGAM5-MAVS interaction regulates TBK1/ IRF3 dependent antiviral responses

Viral infections trigger host innate immune responses, characterized by the production of type-I interferons (IFN) including IFNβ. IFNβ induces cellular antiviral defense mechanisms and thereby contributes to pathogen clearance. Accumulating evidence suggests that mitochondria constitute a crucial p...

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Detalles Bibliográficos
Autores principales:	Yu, Yu-qiang, Zielinska, Marta, Li, Wei, Bernkopf, Dominic B., Heilingloh, Christiane Silke, Neurath, Markus F., Becker, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239892/ https://www.ncbi.nlm.nih.gov/pubmed/32433485 http://dx.doi.org/10.1038/s41598-020-65155-1

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