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The absence of BBSome function decreases synaptogenesis and causes ectopic synapse formation in the retina

Photoreceptors possess ribbon synapses distinct from the conventional synapses in the brain. Little is known about the function of the BBSome, a complex integral in ciliary and intracellular trafficking, in ribbon synaptic formation. We performed immunohistochemistry using retinas from Bardet-Biedl...

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Detalles Bibliográficos
Autores principales: Hsu, Ying, Garrison, Janelle E., Seo, Seongjin, Sheffield, Val C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239920/
https://www.ncbi.nlm.nih.gov/pubmed/32433491
http://dx.doi.org/10.1038/s41598-020-65233-4