Cargando…
The absence of BBSome function decreases synaptogenesis and causes ectopic synapse formation in the retina
Photoreceptors possess ribbon synapses distinct from the conventional synapses in the brain. Little is known about the function of the BBSome, a complex integral in ciliary and intracellular trafficking, in ribbon synaptic formation. We performed immunohistochemistry using retinas from Bardet-Biedl...
Autores principales: | Hsu, Ying, Garrison, Janelle E., Seo, Seongjin, Sheffield, Val C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239920/ https://www.ncbi.nlm.nih.gov/pubmed/32433491 http://dx.doi.org/10.1038/s41598-020-65233-4 |
Ejemplares similares
-
Absence of BBSome function leads to astrocyte reactivity in the brain
por: Singh, Minati, et al.
Publicado: (2019) -
BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment
por: Hsu, Ying, et al.
Publicado: (2017) -
A Novel Protein LZTFL1 Regulates Ciliary Trafficking of the BBSome and Smoothened
por: Seo, Seongjin, et al.
Publicado: (2011) -
The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome
por: Chamling, Xitiz, et al.
Publicado: (2014) -
Intrinsic Protein-Protein Interaction-mediated and Chaperonin-assisted Sequential Assembly of Stable Bardet-Biedl Syndrome Protein Complex, the BBSome
por: Zhang, Qihong, et al.
Publicado: (2012)