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Role of metformin in epigenetic regulation of placental mitochondrial biogenesis in maternal diabetes

Adverse maternal environments, such as diabetes and obesity, impair placental mitochondrial function, which affects fetal development and offspring long-term health. The underlying mechanisms and effective interventions to abrogate such effect remain unclear. Our previous studies demonstrated impair...

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Detalles Bibliográficos
Autores principales: Jiang, Shaoning, Teague, April M., Tryggestad, Jeanie B., Jensen, Mary E., Chernausek, Steven D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239922/
https://www.ncbi.nlm.nih.gov/pubmed/32433500
http://dx.doi.org/10.1038/s41598-020-65415-0