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Administration of apo A-I (Milano) nanoparticles reverses pathological remodelling, cardiac dysfunction, and heart failure in a murine model of HFpEF associated with hypertension

Therapeutic interventions with proven efficacy in heart failure with reduced ejection fraction (HFrEF) have been unsuccessful in heart failure with preserved ejection fraction (HFpEF). The modifiable risk factor with the greatest impact on the development of HFpEF is hypertension. The objectives of...

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Detalles Bibliográficos
Autores principales: Mishra, Mudit, Muthuramu, Ilayaraja, Kempen, Herman, De Geest, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239951/
https://www.ncbi.nlm.nih.gov/pubmed/32433476
http://dx.doi.org/10.1038/s41598-020-65255-y