Preclinical Development and Clinical-Scale Manufacturing of HIV Gag-Specific, LentivirusModified CD4 T Cells for HIV Functional Cure

Activation, infection, and eventual depletion of human immunodeficiency virus (HIV)-specific cluster of differentiation 4 (CD4) T cells are the crucial pathogenetic events in acquired immunodeficiency syndrome (AIDS). We developed a cell and gene therapy to reconstitute HIV-specific CD4 T cells and...

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Detalles Bibliográficos
Autores principales: Li, Haishan, Lahusen, Tyler, Xiao, Lingzhi, Muvarak, Nidal, Blazkova, Jana, Chun, Tae-Wook, Pauza, C. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240062/
https://www.ncbi.nlm.nih.gov/pubmed/32462053
http://dx.doi.org/10.1016/j.omtm.2020.04.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240062/
https://www.ncbi.nlm.nih.gov/pubmed/32462053
http://dx.doi.org/10.1016/j.omtm.2020.04.024

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