Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1

The role of the WDFY1 protein has been studied as a TLR3/4 scaffold/recruiting protein in the immune system and in different oncogenic conditions. However, its function in brain remains poorly understood. We have found that in mice devoid of Helios (He(–/–) mice), a transcription factor specifically...

Descripción completa

Detalles Bibliográficos
Autores principales: Sancho-Balsells, Anna, Brito, Veronica, Fernández, Belissa, Pardo, Mónica, Straccia, Marco, Ginés, Silvia, Alberch, Jordi, Hernández, Isabel, Arranz, Belén, Canals, Josep M., Giralt, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240114/
https://www.ncbi.nlm.nih.gov/pubmed/32477064
http://dx.doi.org/10.3389/fncel.2020.00093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240114/
https://www.ncbi.nlm.nih.gov/pubmed/32477064
http://dx.doi.org/10.3389/fncel.2020.00093

Ejemplares similares