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The Mechanism of β2m Molecule-Induced Changes in the Peptide Presentation Profile in a Bony Fish
Contemporary antigen presentation knowledge is based on the existence of a single β2m locus, and a classical MHC class I forms a complex with a peptide (i.e., pMHC-I) to trigger CTL immunity. However, two β2m loci have been found in diploid bony fish; the function of the two β2m molecules is unclear...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240133/ https://www.ncbi.nlm.nih.gov/pubmed/32438322 http://dx.doi.org/10.1016/j.isci.2020.101119 |