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The Mechanism of β2m Molecule-Induced Changes in the Peptide Presentation Profile in a Bony Fish

Contemporary antigen presentation knowledge is based on the existence of a single β2m locus, and a classical MHC class I forms a complex with a peptide (i.e., pMHC-I) to trigger CTL immunity. However, two β2m loci have been found in diploid bony fish; the function of the two β2m molecules is unclear...

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Detalles Bibliográficos
Autores principales: Li, Zibin, Zhang, Nianzhi, Ma, Lizhen, Zhang, Lijie, Meng, Geng, Xia, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240133/
https://www.ncbi.nlm.nih.gov/pubmed/32438322
http://dx.doi.org/10.1016/j.isci.2020.101119