5-Aza-2′-deoxycytidine advances the epithelial–mesenchymal transition of breast cancer cells by demethylating Sipa1 promoter-proximal elements

Human breast cancer cells exhibit considerable diversity in the methylation status of genomic DNA CpGs that regulate metastatic transcriptome networks. In this study, we identified human Sipa1 promoter-proximal elements that contained a CpG island and demonstrated that the methylation status of the...

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Detalles Bibliográficos
Autores principales: Lu, Ang, Wang, Wei, Wang-Renault, Shu-Fang, Ring, Brian Z., Tanaka, Yoshimasa, Weng, Jun, Su, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240297/
https://www.ncbi.nlm.nih.gov/pubmed/32193333
http://dx.doi.org/10.1242/jcs.236125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240297/
https://www.ncbi.nlm.nih.gov/pubmed/32193333
http://dx.doi.org/10.1242/jcs.236125

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