Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis

Epidermal-specific deletion of integrin α3β1 almost completely prevents the formation of papillomas during 7,12-Dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate (DMBA/TPA) two-stage skin carcinogenesis. This dramatic decrease in tumorigenesis was thought to be due to an egress and prem...

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Detalles Bibliográficos
Autores principales: Ramovs, Veronika, Krotenberg Garcia, Ana, Song, Ji-Ying, de Rink, Iris, Kreft, Maaike, Goldschmeding, Roel, Sonnenberg, Arnoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240742/
https://www.ncbi.nlm.nih.gov/pubmed/32423907
http://dx.doi.org/10.26508/lsa.202000645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240742/
https://www.ncbi.nlm.nih.gov/pubmed/32423907
http://dx.doi.org/10.26508/lsa.202000645

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