Tradeoff between metabolic i-proteasome addiction and immune evasion in triple-negative breast cancer

In vitro studies have suggested proteasome inhibitors could be effective in triple-negative breast cancer (TNBC). We found that bortezomib and carfilzomib induce proteotoxic stress and apoptosis via the unfolded protein response (UPR) in TNBC cell lines, with sensitivity correlated with expression o...

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Bibliographic Details
Main Authors: Adwal, Alaknanda, Kalita-de Croft, Priyakshi, Shakya, Reshma, Lim, Malcolm, Kalaw, Emarene, Taege, Lucinda D, McCart Reed, Amy E, Lakhani, Sunil R, Callen, David F, Saunus, Jodi M
Format: Online Article Text
Language:English
Published: Life Science Alliance LLC 2020
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Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240743/
https://www.ncbi.nlm.nih.gov/pubmed/32423906
http://dx.doi.org/10.26508/lsa.201900562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240743/
https://www.ncbi.nlm.nih.gov/pubmed/32423906
http://dx.doi.org/10.26508/lsa.201900562

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