Tradeoff between metabolic i-proteasome addiction and immune evasion in triple-negative breast cancer

In vitro studies have suggested proteasome inhibitors could be effective in triple-negative breast cancer (TNBC). We found that bortezomib and carfilzomib induce proteotoxic stress and apoptosis via the unfolded protein response (UPR) in TNBC cell lines, with sensitivity correlated with expression o...

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Detalles Bibliográficos
Autores principales: Adwal, Alaknanda, Kalita-de Croft, Priyakshi, Shakya, Reshma, Lim, Malcolm, Kalaw, Emarene, Taege, Lucinda D, McCart Reed, Amy E, Lakhani, Sunil R, Callen, David F, Saunus, Jodi M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
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Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240743/
https://www.ncbi.nlm.nih.gov/pubmed/32423906
http://dx.doi.org/10.26508/lsa.201900562

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