Evaluation of Zhenwu Decoction Effects on CYP450 Enzymes in Rats Using a Cocktail Method by UPLC-MS/MS

This thesis is aimed at shedding light on the effects of the Zhenwu decoction (ZWD) on the activities and mRNA expressions of seven CYP450 isoenzymes. In the first step, we determined the main chemical compounds of ZWD by high-performance liquid chromatography (HPLC). Next, 48 male (SD) rats were ra...

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Detalles Bibliográficos
Autores principales: Hong, Li-li, Wang, Qian, Zhao, Ya-ting, Zhang, Sheng, Zhang, Kai-qi, Chen, Wei-dong, Peng, Can, Liu, Li, Wang, Hong-song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240782/
https://www.ncbi.nlm.nih.gov/pubmed/32461991
http://dx.doi.org/10.1155/2020/4816209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240782/
https://www.ncbi.nlm.nih.gov/pubmed/32461991
http://dx.doi.org/10.1155/2020/4816209

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