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Glycyrrhetinic Acid-Induced MiR-663a Alleviates Hepatic Stellate Cell Activation by Attenuating the TGF-β/Smad Signaling Pathway

Glycyrrhetinic acid (GA), a hydrolysate of glycyrrhizic acid from licorice root extract, has been used to treat liver fibrotic diseases. However, the molecular mechanism involved in the antifibrotic effects of GA remains unclear. The involvement of miR-663a and its roles in TGF-β-1-induced hepatic s...

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Detalles Bibliográficos
Autores principales: Guo, Xin-Xin, Yang, Wen-Na, Dong, Ben-Sheng, Shang, Jia-Wei, Su, Shi-Bing, Yan, Xiu-Li, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240796/
https://www.ncbi.nlm.nih.gov/pubmed/32454854
http://dx.doi.org/10.1155/2020/3156267