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Selective Cyclized α-Melanocyte-Stimulating Hormone Derivative with Multiple N-Methylations for Melanoma Imaging with Positron Emission Tomography

[Image: see text] In this study, we designed and evaluated a novel α-melanocyte-stimulating hormone derivative with four N-methylations for melanocortin 1 receptor-targeted melanoma imaging with positron emission tomography (PET). The resulting peptide, DOTA-Pip-Nle(4)-Cyclo[Asp(5)-N-Me-His(6)-d-Phe...

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Detalles Bibliográficos
Autores principales: Zhang, Chengcheng, Zhang, Zhengxing, Zeisler, Jutta, Colpo, Nadine, Lin, Kuo-Shyan, Bénard, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240809/
https://www.ncbi.nlm.nih.gov/pubmed/32455196
http://dx.doi.org/10.1021/acsomega.0c00310