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Molecular mechanisms, off‐target activities, and clinical potentials of genome editing systems

Methodologies of genome editing are rapidly developing with the improvement of gene science and technology, mechanism‐based understanding, and urgent needs. In addition to the specificity and efficiency of on‐target sites, one of the most important issues is to find and avoid off‐targets before clin...

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Detalles Bibliográficos
Autores principales: Zheng, Nannan, Li, Liyang, Wang, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240848/
https://www.ncbi.nlm.nih.gov/pubmed/32508055
http://dx.doi.org/10.1002/ctm2.34