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Molecular mechanisms, off‐target activities, and clinical potentials of genome editing systems
Methodologies of genome editing are rapidly developing with the improvement of gene science and technology, mechanism‐based understanding, and urgent needs. In addition to the specificity and efficiency of on‐target sites, one of the most important issues is to find and avoid off‐targets before clin...
Autores principales: | Zheng, Nannan, Li, Liyang, Wang, Xiangdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240848/ https://www.ncbi.nlm.nih.gov/pubmed/32508055 http://dx.doi.org/10.1002/ctm2.34 |
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