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The Inhibition Kinetics and Potential Anti-Migration Activity of NQO1 Inhibitory Coumarins on Cholangiocarcinoma Cells

Altered expression of a cytosolic flavoenzyme NAD(P)H:quinone oxidoreductase-1 (NQO1) has been seen in many human tumors. Its remarkable overexpression in cholangiocarcinoma (CCA; an aggressive malignancy of the biliary duct system) was associated with poor prognosis and short survival of the patien...

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Detalles Bibliográficos
Autores principales: Khunluck, Tueanjai, Kukongviriyapan, Veerapol, Senggunprai, Laddawan, Duangarsong, Wutthipong, Prawan, Auemduan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240875/
https://www.ncbi.nlm.nih.gov/pubmed/30584780
http://dx.doi.org/10.1177/1534735418820444