An integrative investigation on significant mutations and their down-stream pathways in lung squamous cell carcinoma reveals CUL3/KEAP1/NRF2 relevant subtypes

BACKGROUND: Molecular mechanism of lung squamous cell carcinoma (LUSC) remains poorly understood, hampering effective targeted therapies or precision diagnosis about LUSC. We devised an integrative framework to investigate on the molecular patterns of LUSC by systematically mining the genomic, trans...

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Detalles Bibliográficos
Autores principales: Liu, Zongang, Deng, Meiyan, Wu, Lin, Zhang, Suning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240936/
https://www.ncbi.nlm.nih.gov/pubmed/32434476
http://dx.doi.org/10.1186/s10020-020-00166-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240936/
https://www.ncbi.nlm.nih.gov/pubmed/32434476
http://dx.doi.org/10.1186/s10020-020-00166-2

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