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Development and optimization of orthotopic liver metastasis xenograft mouse models in uveal melanoma

BACKGROUND: Patients with metastatic uveal melanoma (MUM) in the liver usually die within 1 year. The development of new treatments for MUM has been limited by the lack of diverse MUM cell lines and appropriate animal models. We previously reported that orthotopic xenograft mouse models established...

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Detalles Bibliográficos
Autores principales: Sugase, Takahito, Lam, Bao Q., Danielson, Meggie, Terai, Mizue, Aplin, Andrew E., Gutkind, J. Silvio, Sato, Takami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240939/
https://www.ncbi.nlm.nih.gov/pubmed/32434572
http://dx.doi.org/10.1186/s12967-020-02377-x