Metabolic Fingerprinting with Fourier-Transform Infrared (FTIR) Spectroscopy: Towards a High-Throughput Screening Assay for Antibiotic Discovery and Mechanism-of-Action Elucidation

The discovery of antibiotics has been slowing to a halt. Phenotypic screening is once again at the forefront of antibiotic discovery, yet Mechanism-Of-Action (MOA) identification is still a major bottleneck. As such, methods capable of MOA elucidation coupled with the high-throughput screening of wh...

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Detalles Bibliográficos
Autores principales: Ribeiro da Cunha, Bernardo, Fonseca, Luís P., Calado, Cecília R.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240953/
https://www.ncbi.nlm.nih.gov/pubmed/32283661
http://dx.doi.org/10.3390/metabo10040145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7240953/
https://www.ncbi.nlm.nih.gov/pubmed/32283661
http://dx.doi.org/10.3390/metabo10040145

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