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Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein

BACKGROUND: We have proved fecal microbiota transplantation (FMT) is an efficacious remedy to mitigate acute radiation syndrome (ARS); however, the mechanisms remain incompletely characterized. Here, we aimed to tease apart the gut microbiota-produced metabolites, underpin the therapeutic effects of...

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Detalles Bibliográficos
Autores principales: Xiao, Hui-wen, Cui, Ming, Li, Yuan, Dong, Jia-li, Zhang, Shu-qin, Zhu, Chang-chun, Jiang, Mian, Zhu, Tong, Wang, Bin, Wang, Hai-Chao, Fan, Sai-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241002/
https://www.ncbi.nlm.nih.gov/pubmed/32434586
http://dx.doi.org/10.1186/s40168-020-00845-6