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ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in December 2019(1,2) and is responsible for the COVID-19 pandemic(3). Vaccines are an essential countermeasure urgently needed to control the pandemic(4). Here, we show that the adenovirus-vectored vaccine ChAdOx1 nCoV-19, encodin...

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Detalles Bibliográficos
Autores principales: van Doremalen, Neeltje, Lambe, Teresa, Spencer, Alexandra, Belij-Rammerstorfer, Sandra, Purushotham, Jyothi N., Port, Julia R., Avanzato, Victoria, Bushmaker, Trenton, Flaxman, Amy, Ulaszewska, Marta, Feldmann, Friederike, Allen, Elizabeth R., Sharpe, Hannah, Schulz, Jonathan, Holbrook, Myndi, Okumura, Atsushi, Meade-White, Kimberly, Pérez-Pérez, Lizzette, Bissett, Cameron, Gilbride, Ciaran, Williamson, Brandi N., Rosenke, Rebecca, Long, Dan, Ishwarbhai, Alka, Kailath, Reshma, Rose, Louisa, Morris, Susan, Powers, Claire, Lovaglio, Jamie, Hanley, Patrick W., Scott, Dana, Saturday, Greg, de Wit, Emmie, Gilbert, Sarah C., Munster, Vincent J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241103/
https://www.ncbi.nlm.nih.gov/pubmed/32511340
http://dx.doi.org/10.1101/2020.05.13.093195