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Pharmacological STING Activation Is a Potential Alternative to Overcome Drug-Resistance in Melanoma

Melanoma is the most aggressive type of skin cancer and resistance to the conventional chemotherapy is the major cause for its poor prognosis. Metabolic perturbations leading to increased production of reactive oxygen species activate NRF2-dependent anti-oxidative responses to survive oxidative stre...

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Detalles Bibliográficos
Autores principales: Chipurupalli, Sandhya, Ganesan, Raja, Dhanabal, S. P., Kumar, M. Suresh, Robinson, Nirmal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241280/
https://www.ncbi.nlm.nih.gov/pubmed/32477956
http://dx.doi.org/10.3389/fonc.2020.00758