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Synthesis and carbonic anhydrase activating properties of a series of 2-amino-imidazolines structurally related to clonidine(1)

The Carbonic Anhydrase (CA, EC 4.2.1.1) activating properties of histamine have been known for a long time. This compound has been extensively modified but only in few instances the imidazole ring has been replaced with other heterocycles. It was envisaged that the imidazoline ring could be a bioiso...

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Detalles Bibliográficos
Autores principales: Chiaramonte, Niccolò, Maach, Soumia, Biliotti, Caterina, Angeli, Andrea, Bartolucci, Gianluca, Braconi, Laura, Dei, Silvia, Teodori, Elisabetta, Supuran, Claudiu T., Romanelli, Maria Novella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241460/
https://www.ncbi.nlm.nih.gov/pubmed/32336172
http://dx.doi.org/10.1080/14756366.2020.1749602