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Interleukin-22 attenuates renal tubular cells inflammation and fibrosis induced by TGF-β1 through Notch1 signaling pathway

Transforming growth factor-β1 (TGF-β1) is a crucial factor implicated in the development of renal inflammation and tubulointerstitial fibrosis (TIF). The cytokine interleukin 22 (IL-22) was previously reported to involve in the pathogenesis of chronic inflammatory diseases, however recent studies sh...

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Detalles Bibliográficos
Autores principales: Tang, Rong, Xiao, Xiangcheng, Lu, Yang, Li, Huihui, Zhou, Qiaoling, Kwadwo Nuro-Gyina, Patrick, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241524/
https://www.ncbi.nlm.nih.gov/pubmed/32338120
http://dx.doi.org/10.1080/0886022X.2020.1753538