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Small heat shock proteins determine synapse number and neuronal activity during development

Environmental changes cause stress, Reactive Oxygen Species and unfolded protein accumulation which hamper synaptic activity and trigger cell death. Heat shock proteins (HSPs) assist protein refolding to maintain proteostasis and cellular integrity. Mechanisms regulating the activity of HSPs include...

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Detalles Bibliográficos
Autores principales: Santana, Elena, de los Reyes, Teresa, Casas-Tintó, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7241713/
https://www.ncbi.nlm.nih.gov/pubmed/32437379
http://dx.doi.org/10.1371/journal.pone.0233231